Unlocking the Power of Hovenia dulcis: How WakeFresh Overcomes Bioavailability Challenges for Faster Relief
- 1 min reading time
Hovenia dulcis, also known as DHM, has a long history of use in traditional Asian medicine, particularly in Japan, China, and Korea. It has been used to treat a variety of ailments, including fever, parasitic infections, liver diseases, and as a laxative. DHM is also known for its effectiveness as a hangover remedy. Research has been conducted to explore its potential as a medicinal compound, with particular interest in ampelopsin, a bioactive component that can now be extracted on a larger scale. Laboratory studies are investigating whether this compound could be developed into a treatment for the conditions traditionally treated with the Hovenia dulcis plant.
One of the challenges with Dihydromyricetin (DHM) is its poor bioavailability, which limits its effectiveness as a medicinal agent. Bioavailability refers to the fraction of a drug that enters the bloodstream after administration, with intravenous delivery achieving 100% bioavailability. However, when medications are taken by other routes, such as oral administration, the absorption is reduced due to factors like intestinal absorption and first-pass metabolism in the liver.
To overcome the bioavailability issue, WakeFresh has been developed to be absorbed through the sublingual mucosa (under the tongue), bypassing the gastrointestinal tract and liver. Sublingual administration offers several advantages:
- Faster onset: Medications absorbed sublingually enter the bloodstream more quickly than oral medications, providing faster relief, which can be particularly beneficial for treatments where rapid action is needed.
- No swallowing required: This delivery method is helpful for individuals who have difficulty swallowing pills, offering a convenient alternative that doesn’t require ingestion.
By utilizing sublingual absorption, WakeFresh maximizes the effectiveness of DHM and provides a faster, more efficient route of administration.
